管清美，女，山东诸城人。博士，教授，博士生导师。2002年毕业于西北农林科技大学果树专业，获农学学士学位；2005年毕业于西北农林科技大学果树专业，获硕士学位；2013年毕业于美国马里兰大学植物学专业，获博士学位。2005年-2008年在蚌埠学院任助教、讲师；2013-2014年在美国马里兰大学进行博士后研究工作；2014年到西北农林科技大学园艺学院工作。入选第十一批“人才项目专家”青年人才计划、陕西省第八批“百人计划”；主持国家自然科学基金面上、优秀青年科学基金项目、中组部国家青年人才项目项目、陕西省百人、创新人才推进计划项目。

联系方式：

　　Email: qguan@nwafu.edu.cn

    学院网个人简介链接：http://yyxy.nwsuaf.edu.cn/szdw/258218.htm

研究方向：

　　苹果耐非生物逆境（干旱、低温）的分子机制；苹果基因组学；苹果基因组设计育种。

重点内容：

　　针对西北地区黄土高原苹果产区所面临的非生物逆境，利用苹果基因组学、功能基因组学、分子生物学的手段解析苹果响应非生物逆境的分子机制，以此为基础改良和创制苹果抗逆新种质。

代表性论著和成果：（^*通讯作者，^#第一作者）

1. Liu X, Zhao C, Gao Y, Wang S, Li C, Xie Y, Chen P, Wang X, Huang L, Ma F, Feng H*, Guan Q*. (2020) A multifaceted module of MdBES1-MdMYB88 in plant growth and stress tolerance. Plant Physiology. 185(4):1903-1923. doi: 10.1093/plphys/kiaa116.

2. Zhang D, Yang K, Kan Z, Dang H, Feng S, Yang Y, Li L, Hou N, Xu L, Wang X, Malnoy M, Ma F, Hao Y*, Guan Q*. (2020) The regulatory module MdBT2–MdMYB88/MdMYB124–MdNRTs regulates nitrogen usage in Apple. Plant Physiology. 185(4):1924-1942. doi: 10.1093/plphys/kiaa118.

3. Chen P, Yan M, Li L, He J, Zhou S, Li Z, Niu C, Bao C, Zhi F, Ma F, Guan Q*. (2020) The apple DNA-binding one zinc-finger protein MdDof54 promotes drought resistance. Hortic Res. 7:195

4. Xie Y#, Bao C#, Chen P#, Cao F, Liu X, Geng D, Li Z, Li X, Hou N, Zhi F, Niu C, Zhou S, Zhan X, Ma F, Guan Q*. (2020) ABA homeostasis is mediated by a feedback regulation of MdMYB88 and MdMYB124. J Exp Bot. 72(2):592-607. doi: 10.1093/jxb/eraa449.

5. Li X#, Chen P#, Xie Y, Yan Y, Wang L, Dang H, Zhang J, Xu L, Ma F, Guan Q*. (2020) Hortic Res. Apple SERRATE negatively mediates drought resistance by regulating MdMYB88 and MdMYB124 and microRNA biogenesis. Hortic Res. 7:98.

6. Geng D#, Shen X#, Xie Y, Yang Y, Bian R, Gao Y, Li P, Sun L, Feng H, Ma F, Guan Q*. (2020) Regulation of phenylpropanoid biosynthesis by MdMYB88 and MdMYB124 contributes to pathogen and drought resistance in apple. Hortic Res. 7:102.

7. Zhao C#, Liu X#, He J, Xie Y, Xu Y, Ma F, Guan Q*. (2020) Apple TIME FOR COFFEE contributes to freezing tolerance by promoting unsaturation of fatty acids. Plant Science. 302:110695. doi: 10.1016/j.plantsci.2020.110695.

8. Geng D, Li L, Yang Y, Ma F, Guan Q*. (2020) Factors Affecting Hydraulic Conductivity and Methods to Measure in Plants. Journal of Integrative Agriculture. Accepted.

9. Niu C, Li H, Jiang L, Yan M, Li C, Geng D, Xie Y, Yan Y, Shen X, Chen P, Dong J, Ma F, Guan Q*. (2019). Genome-wide identification of drought-responsive microRNAs in two sets of Malus  from interspecific hybrid progenies. Hort Res. 6:75.

10. Li X #, Xie Y #, Lu L, Yan M, Fang, N, Xu J, Wang L, Yan Y, Zhao T, van Nocker, S, Ma F, Liang D*, Guan Q*.  (2019). Contribution of methylation regulation of MpDREB2A promoter to drought resistance of Mauls prunifolia . Plant and Soil, 441(1), 15.

11. Geng D, Lu L, Yan M, Shen X, Jiang L, Li H, Wang L, Yan Y, Xu J, Li C, Yu J, Ma F, Guan Q*. (2019). Physiological and transcriptomic analyses of roots from Malus sieversii  under drought stress. Journal of Integrative Agriculture, 18(6): 1280-1294.

12. Zhai R, Wang Z, Yang C, Lin-Wang K, Espley R, Liu J, Li X, Wu Z, Li P, Guan Q, Ma F, Xu L*. (2019). PbGA2ox8 induces vascular-related anthocyanin accumulation and contributes to red stripe formation on pear fruit. Hortic Res. 6:137.

13. Zhao XY, Qi CH, Jiang H, You CX, Guan QM, Ma FW, Li YY, Hao YJ. (2019). The MdWRKY31 transcription factor binds to the MdRAV1 promoter to mediate ABA sensitivity. Hortic Res. 6:66.

14. Guo T, Wang N, Xue Y, Guan Q, van Nocker S, Liu C, Ma F*. (2019). Overexpression of the RNA binding protein MhYTP1 in transgenic apple enhances drought tolerance and WUE by improving ABA level under drought condition. Plant Sci. 280:397-407.

15. Geng, D., Chen, P., Shen, X., Zhang, Y., Li, X., Jiang, L., Xie, Y., Niu, C., Zhang, J., Huang, X., Ma, F., Guan, Q*. (2018). MdMYB88 and MdMYB124 Enhance Drought Tolerance by Modulating Root Vessel and Cell Wall in Apple. Plant Physiology. 178(3):1296-1309.

16. Xie, Y., Chen, P., Yan, Y., Bao, C., Li, X., Wang, L., Shen, X., Li, H.; Liu, X., Niu, C., Zhu, C., Fang, N., Shao, Y., Zhao, T., Yu, J., Zhu, J., Xu, L., van Nocker, S., Ma, F., Guan, Q*. (2018). An Atypical R2R3 MYB Transcription Factor Increases Cold Hardiness by CBF-Dependent and CBF-Independent Pathways in Apple. New Phytologist. 218(1):201-218.

17. Xu, J., Zhou, S., Gong, X., Song, Y., van Nocker, S., Ma, F.*, Guan, Q*. (2018). Single-base methylome analysis reveals dynamic epigenomic differences associated with water deficit in apple. Plant Biotechnology Journal. 16(2):672-687.

18. Li, X. #, Kui, L. #, Zhang, J., Xie, Y., Wang, L., Yan, Y., Wang, N., Xu, J., Li, C., Wang, W., van Nocker, S., Dong, Y. *, Ma, F. *, and Guan, Q*. (2016). Improved hybrid de novo genome assembly of domesticated apple (Malus x domestica). Gigascience. 5(1):35.

19. Zhou, S. #, Li, M. #, Guan, Q., Liu, F., Zhang F., Chen, W., Yin, L., Qin, Y., and Ma, F*. (2015) Physiological and proteome analysis suggest critical roles for the photosynthetic system for high water-use efficiency under drought stress in Malus . Plant Science. 236:44-60.

20. Zhan X*, Qian B, Cao F, Wu W, Yang L, Guan Q, Gu X, Wang P, Okusolubo TA, Dunn SL, Zhu JK, Zhu, J*. (2015). An Arabidopsis PWI and RRM motif-containing protein is critical for pre-mRNA splicing and ABA responses. Nature Communications. 6:8139.

21. Guan, Q., Yue, X., Zeng, H., and Zhu, J*. (2014). The protein phosphatase and its interacting partner NAC019 are required for heat stress-responsive gene regulation and thermotolerance in Arabidopsis. Plant Cell. 26(1):438-453.

22. Guan, Q., Wu, J., Yue, X., Zhang, Y., and Zhu, J*. (2013). A nuclear calcium-sensing pathway is critical for gene regulation and salt stress tolerance in Arabidopsis. PLoS Genetics. 9(8): e1003755.

23. Guan, Q., Wu, J., Zhang, Y., Jiang, C., Liu, R., Chai, C., and Zhu, J*. (2013). A DEAD box RNA helicase is critical for pre-mRNA splicing, cold-responsive gene regulation, and cold tolerance in Arabidopsis. Plant Cell. 25: 342-356.

24. Guan, Q., Lu, X., Zeng, H., Zhang, Y., and Zhu, J*. (2013). Heat stress induction of miR398 triggers a regulatory loop that is critical for thermotolerance in Arabidopsis. Plant Journal. 74: 840-851.

25. Guan, Q., Wen, C., Zeng, H., and Zhu, J*. (2013). A KH domain-containing putative RNA-binding protein is critical for heat stress-responsive gene regulation and thermotolerance in Arabidopsis. Molecular Plant. 6: 386-395.

26. Li, W.#, Guan, Q.# (co-first author), Wang, Z.-Y., Wang, Y., and Zhu, J*. (2013). A bi-functional xyloglucan galactosyltransferase is an indispensable salt stress tolerance determinant in Arabidopsis. Molecular Plant. 6: 1344-1354.

27. Lu, X., Guan, Q., and Zhu, J*. (2013). Downregulation of CSD2 by a heat-inducible miR398 is required for thermotolerance in Arabidopsis. Plant Signaling & Behavior. 8(8). pii: e24952.

28. Jeong, S.I., Fukudome, A., Aksoy, E., Bang, W.Y., Kim, S., Guan, Q., Bahk, J.D., May, A.K., Russell, W.K., Zhu, J., Koiwa, H*. (2013). Regulation of Abiotic Stress Signaling by Arabidopsis C-terminal Domain Phosphatase-like 1 Requires Interaction with a K-homology Domain-containing Protein. PLoS ONE. 8(11): e80509.